DNA Binding Motif

						

			
Accessions: CUX1_DBD_3 (HumanTF 1.0), MA0754.1 (JASPAR 2024)

			
Names: CUX1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 3, HT-SELEX
Length: 10
Consensus: TrATCrATam
Weblogo: 
PSSM: P0      A      C      G      T
01   4099   4649   2401  25659      T
02  25659   3296  15550   7605      r
03  25659    109    192    167      A
04     71    294     77  25659      T
05     51  25659     53    595      C
06   9580    264  16079    130      r
07  25659     45     85    231      A
08    150     95     29  25659      T
09  25659   9420   7560   7079      a
10   8168   7633   3958   5900      m
Type: Heterodimer
Binding TFs: CUX1_DBD (Homeobox domain, CUT domain, Homeobox KN domain)
P39880 (Homeobox domain, CUT domain, Homeobox KN domain)
P39880
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Harada R., Berube G., Tamplin O. J., Denis-Larose C., Nepveu A. DNA-binding specificity of the cut repeats from the human cut-like protein. Mol. Cell. Biol. 15:129-140 (1995). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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