DNA Binding Motif

						

			
Accessions: TFAP2C_ETV7 (HumanTF2 1.0)

			
Names: TFAP2C_ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 26
Consensus: sCYbsrGGssrcGGAAgyvytTCCks
Weblogo: 
PSSM: P0      A      C      G      T
01     33    154    226     22      s
02      0    380      5      7      C
03      3    380     17    148      Y
04     24    133     98    124      b
05     70    133    109     68      s
06    130     64    141     45      r
07    106     11    380      0      G
08      0     16    380      1      G
09     51    180    200     34      s
10     60    117    109     94      s
11    175     62    101     41      r
12     63    145     88     84      c
13     40      0    380      1      G
14      0      0    380      0      G
15    380      5      1     32      A
16    380     61      3     68      A
17    136    119    380     21      g
18     40    121     64    155      y
19    129     95    100     55      v
20     19    189     71    101      y
21    100      6    118    380      t
22     53      1     19    380      T
23      5    380      7      2      C
24     10    380      3     39      C
25     56     77    152     95      k
26     67    124    116     73      s
Type: Heterodimer
Binding TFs: TFAP2C_TF1 (Transcription factor AP-2)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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