DNA Binding Motif

Accessions: 1jk2_A (3D-footprint 20231221)
Names: ZIF268
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Zif268 D20A mutant bound to the GCT DNA site
Length: 8
Consensus: GCGtGGGC
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 1 76 0 19 C
03 0 0 96 0 G
04 20 19 19 38 t
05 0 0 96 0 G
06 0 0 96 0 G
07 0 0 96 0 G
08 0 96 0 0 C
Binding TFs: 1jk2_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 1jk2_B
1jk2_C
Publications: Miller J.C, Pabo C.O. Rearrangement of side-chains in a Zif268 mutant highlights the complexities of zinc finger-DNA recognition. Journal of molecular biology 313:309-15 (2001). [Pubmed]

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