DNA Binding Motif

Accessions: HOXD12_EOMES_2 (HumanTF2 1.0)
Names: HOXD12_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: tTwAYGAkswwCmTCGTwAA
Weblogo:
PSSM: P0 A C G T
01 79 36 61 238 t
02 37 23 22 331 T
03 178 1 32 203 w
04 414 0 2 18 A
05 12 414 17 165 Y
06 22 18 414 9 G
07 414 0 12 29 A
08 21 48 221 123 k
09 0 135 273 10 s
10 194 39 34 147 w
11 222 27 23 143 w
12 0 331 100 0 C
13 139 200 84 0 m
14 34 2 37 414 T
15 34 414 0 21 C
16 122 14 414 3 G
17 0 0 4 414 T
18 246 25 0 156 w
19 306 2 24 82 A
20 290 45 21 58 A
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
HOXD12_TF1 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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