DNA Binding Motif

						

			
Accessions: TEAD4_HOXA13_2_3_4 (HumanTF2 1.0)

			
Names: TEAD4_HOXA13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: rCATwCcdmrswaTTTAyrag
Weblogo: 
PSSM: P0      A      C      G      T
01    112     28    151      9      r
02     42    263     23      0      C
03    263      1     38      4      A
04      2      4      3    263      T
05    101     11     33    162      w
06     19    263     52     38      C
07     19    263     15     92      c
08     93     32     73     66      d
09     72     88     53     50      m
10     74     55     70     64      r
11     58     85     70     50      s
12     83     61     50     70      w
13    129     24     54     55      a
14     25     19     42    263      T
15     22     14     22    263      T
16     43     31     12    263      T
17    263      0     18     23      A
18     19    160     10    103      y
19     71     10    133     49      r
20    163     12     64     24      a
21     22     63    147     31      g
Type: Heterodimer
Binding TFs: HOXA13_TF2 (Homeobox domain, Hox protein A13 N terminal)
HOXA13_Full (Homeobox domain, Hox protein A13 N terminal)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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