DNA Binding Motif

						

			
Accessions: 4lln_I (3D-footprint 20231221)

			
Names: MepR
Organisms: Staphylococcus aureus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of S. aureus MepR-DNA complex
Length: 9
Consensus: TCTAAnnAA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      7     73      7      9      C
03      0      0      0     96      T
04     73      7      7      9      A
05     75      7      7      7      A
06     24     24     24     24      n
07     24     24     24     24      n
08     75      7      7      7      A
09     96      0      0      0      A
Binding TFs: 4lln_I (MarR family, MarR family, Winged helix-turn-helix DNA-binding, Winged helix DNA-binding domain)
Binding Sites: 4lln_K / 4lln_L
			
Publications: Birukou I, Seo S.M, Schindler B.D, Kaatz G.W, Brennan R.G. Structural mechanism of transcription regulation of the Staphylococcus aureus multidrug efflux operon mepRA by the MarR family repressor MepR. Nucleic acids research 42:2774-88 (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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