DNA Binding Motif

Accessions: FOXO1_HOXB13_1 (HumanTF2 1.0)
Names: FOXO1_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: vwmmACAmmcymrTaAA
Weblogo:
PSSM: P0 A C G T
01 314 228 289 16 v
02 145 43 24 143 w
03 100 189 9 19 m
04 289 126 0 21 m
05 289 7 34 7 A
06 17 289 1 69 C
07 289 10 14 16 A
08 103 102 24 60 m
09 93 88 71 37 m
10 54 201 88 28 c
11 39 156 8 133 y
12 137 152 6 63 m
13 192 10 96 14 r
14 0 10 1 289 T
15 289 23 16 98 a
16 289 0 3 23 A
17 289 69 15 46 A
Type: Heterodimer
Binding TFs: FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.