DNA Binding Motif

Accessions: ERF_DLX3_1 (HumanTF2 1.0)
Names: ERF_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: avmGGAwryrgsyamTtr
Weblogo:
PSSM: P0 A C G T
01 165 85 99 113 a
02 123 149 114 46 v
03 122 264 38 0 m
04 0 0 264 6 G
05 15 5 264 0 G
06 264 16 1 20 A
07 264 20 31 131 w
08 99 54 79 32 r
09 31 96 40 98 y
10 75 54 110 25 r
11 58 42 102 61 g
12 33 67 119 45 s
13 84 143 55 121 y
14 264 55 94 125 a
15 264 120 44 34 m
16 28 7 14 264 T
17 24 57 47 264 t
18 264 51 183 124 r
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
ERF_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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