DNA Binding Motif

						

			
Accessions: FLI1_DLX2_1 (HumanTF2 1.0)

			
Names: FLI1_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: rsMGGAAryaaTtA
Weblogo: 
PSSM: P0      A      C      G      T
01    141     20     83     20      r
02     73    132     92     22      s
03     91    224      0      0      M
04      0      7    224      0      G
05      9      0    224     53      G
06    224      1      0      0      A
07    224      0      0     38      A
08    116      0    108      7      r
09      8     80     31    144      y
10    224     74     38     24      a
11    224     35     47     55      a
12     14     33     28    224      T
13     76     15     78    224      t
14    224     18     30     41      A
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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