DNA Binding Motif

						

			
Accessions: FOXO1_HOXB13_2 (HumanTF2 1.0)

			
Names: FOXO1_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: rwmAACAymrTwAA
Weblogo: 
PSSM: P0      A      C      G      T
01    286    198    294     32      r
02     99     52     48    195      w
03    151    143      0     22      m
04    294     47      0     15      A
05    294     26     41     17      A
06      1    294     10     49      C
07    294     41     52      6      A
08     13    104      6    190      y
09     88    207     16     30      m
10    126      6    168     23      r
11      3     14      8    294      T
12    294     13     17    145      w
13    294      4      0     28      A
14    294     44     11     40      A
Type: Heterodimer
Binding TFs: FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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