DNA Binding Motif

						

			
Accessions: 2ayb_AB (3D-footprint 20231221)

			
Names: Regulatory protein E2
Organisms: Human papillomavirus type 6a
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of HPV6a E2 DNA Binding Domain bound to a 16 base pair DNA target
Length: 16
Consensus: CAACCGnnnnCGGTTG
Weblogo: 
PSSM: P0      A      C      G      T
01      5     81      5      5      C
02     96      0      0      0      A
03     80      5      6      5      A
04      0     96      0      0      C
05      0     96      0      0      C
06      5      6     80      5      G
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11      5     80      5      6      C
12      0      0     96      0      G
13      0      0     96      0      G
14      5      5      5     81      T
15      0      0      0     96      T
16      5      5     81      5      G
Binding TFs: 2ayb_A / 2ayb_B (E2 (early) protein, C terminal)
Binding Sites: 2ayb_C / 2ayb_D
			
Publications: Hooley E, Fairweather V, Clarke A.R, Gaston K, Brady R.L. The recognition of local DNA conformation by the human papillomavirus type 6 E2 protein. Nucleic acids research 34:3897-908 (2006). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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