DNA Binding Motif

						

			
Accessions: MA0143.2 (JASPAR 2024)

			
Names: Sox2
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 15
Consensus: cywTTGTyaTgcaaA
Weblogo: 
PSSM: P0      A      C      G      T
01     27    446     89    107      c
02     20    454     22    173      y
03    329      6      3    331      w
04      2     10      6    651      T
05     14      0      6    649      T
06     36     83    531     19      G
07     85      4      8    571      T
08     63    195     76    334      y
09    407    125     38     96      a
10     26     37     26    577      T
11     26     77    445    117      g
12     31    423     84    127      c
13    426     42     37    159      a
14    367     67    156     74      a
15    485     60     59     58      A
Type: Heterodimer
Binding TFs: P48432 (HMG (high mobility group) box, Domain of unknown function (DUF1898), SOX transcription factor)
P48432
			
Publications: Chen X, Xu H, Yuan P, Fang F, Huss M, Vega V.B, Wong E, Orlov Y.L, Zhang W, Jiang J, Loh Y.H, Yeo H.C, Yeo Z.X, Narang V, Govindarajan K.R, Leong B, Shahab A, Ruan Y, Bourque G, Sung W.K, Clarke N.D, Wei C.L, Ng H.H. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133:1106-17 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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