DNA Binding Motif

						

			
Accessions: HOXB2_PAX5_2 (HumanTF2 1.0)

			
Names: HOXB2_PAX5
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: vhmaTTaGTCACGCwTsrcTG
Weblogo: 
PSSM: P0      A      C      G      T
01    888    871   1194    290      v
02    848    878    560    957      h
03   1097   1826    601    540      m
04   3023    470    969    246      a
05     43    139     43   3201      T
06    140   1010    124   2885      T
07   2939    670    242    559      a
08     13      0   3233     34      G
09    224    139     24   3083      T
10     58   3190      2    308      C
11   3209     32     90     45      A
12      0   3076      0    520      C
13    132      4   3226      0      G
14      1   2990    883      9      C
15   1622    143    190   1591      w
16    152    918      0   2990      T
17      4   1408   1838     15      s
18   2143     31   1105      4      r
19    640   1390    611    601      c
20    123    854     41   2959      T
21    927      0   2949    119      G
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
PAX5_TF1 / PAX5_TF2 ('Paired box' domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.