DNA Binding Motif

						

			
Accessions: MA0620.2 (JASPAR 2024)

			
Names: MITF
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 18
Consensus: wrwrGTCACGTGACywyw
Weblogo: 
PSSM: P0      A      C      G      T
01   6144   5716   5659   6434      w
02   6284   5693   6007   5969      r
03   9602   3102   4896   6353      w
04   6516   1815  11196   4426      r
05   4909   1841  16735    468      G
06    750   1704    957  20542      T
07     50  23756    103     44      C
08  23521    137     76    219      A
09     54  18655    347   4897      C
10   4898    347  18654     54      G
11    219     76    137  23521      T
12     44    103  23757     49      G
13  20547    956   1702    748      A
14    468  16737   1842   4906      C
15   4426  11194   1815   6518      y
16   6354   4895   3103   9601      w
17   5970   6004   5694   6285      y
18   6436   5659   5714   6144      w
Type: Heterodimer
Binding TFs: O75030 (Helix-loop-helix DNA-binding domain, Domain of unknown function (DUF3371))
O75030
Binding Sites: MA0620.2.1
MA0620.2.10
MA0620.2.11
MA0620.2.12
MA0620.2.13
MA0620.2.14
MA0620.2.15
MA0620.2.16
MA0620.2.17
MA0620.2.18
MA0620.2.19
MA0620.2.2
MA0620.2.20
MA0620.2.3
MA0620.2.4
MA0620.2.5
MA0620.2.6
MA0620.2.7
MA0620.2.8
MA0620.2.9
			
Publications: McGill G. G., Horstmann M., Widlund H. R., Du J., Motyckova G., Nishimura E. K., Lin Y. L., Ramaswamy S., Avery W., Ding H. F., Jordan S. A., Jackson I. J., Korsmeyer S. J., Golub T. R., Fisher D. E. Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.. Cell 109:707-718 (2002). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.