DNA Binding Motif

						

			
Accessions: 4hn5_AB (3D-footprint 20231221)

			
Names: Glucocorticoid receptor
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: GR DNA Binding Domain - TSLP nGRE Complex
Length: 8
Consensus: CCnGnnGC
Weblogo: 
PSSM: P0      A      C      G      T
01      0     96      0      0      C
02     11     67      9      9      C
03     24     24     24     24      n
04      9      9     67     11      G
05     24     24     24     24      n
06     24     24     24     24      n
07      9     11     67      9      G
08      0     96      0      0      C
Type: Heterodimer
Binding TFs: 4hn5_A (Zinc finger, C4 type (two domains))
4hn5_B (Zinc finger, C4 type (two domains))
Binding Sites: 4hn5_C
4hn5_D
			
Publications: Hudson W.H, Youn C, Ortlund E.A. The structural basis of direct glucocorticoid-mediated transrepression. Nature structural & molecular biology 20:53-8 (2013). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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