DNA Binding Motif

						

			
Accessions: POU2F1_EOMES_2 (HumanTF2 1.0)

			
Names: POU2F1_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rgTGtwrgaATATkcm
Weblogo: 
PSSM: P0      A      C      G      T
01   1384    610   1727    985      r
02    401   1150   3111    766      g
03    217    948    234   3111      T
04    288     10   3111    264      G
05   1390   1138    353   3111      t
06    913    439    684   1075      w
07   1487    285    888    450      r
08    403    280   2023    405      g
09   3111   1192    297    303      a
10   3111     55      0    495      A
11      0     28     16   3111      T
12   3111      0     17     49      A
13    301     54     52   3111      T
14    187    114   1162   1949      k
15    450   2035    229    397      c
16    866   1149    472    625      m
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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