DNA Binding Motif

						

			
Accessions: POU2F1_EOMES_2_3 (HumanTF2 1.0)

			
Names: POU2F1_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 24
Consensus: akGTGtwkGmATATkymyrCrswg
Weblogo: 
PSSM: P0      A      C      G      T
01    499    214    257    199      a
02     87     78    413    235      k
03      0     48    499     91      G
04      0     13      1    499      T
05     53      0    499      0      G
06    146    149    100    499      t
07    184     48     40    227      w
08     77     15    256    152      k
09     65      6    399     28      G
10    499    243      6      0      m
11    499      5      0     26      A
12      0      1      0    499      T
13    499      0      0      0      A
14     10      0     34    499      T
15     22      0    237    262      k
16     78    282     87    217      y
17    168    193     22    117      m
18     68    219     33    179      y
19    281      3    197     18      r
20     24    499      1      3      C
21    296      5    203     32      r
22     35    499    250     58      s
23    131     54     56    258      w
24     30    114    232    124      g
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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