DNA Binding Motif

						

			
Accessions: 2irf_GH (3D-footprint 20231221)

			
Names: INTERFERON REGULATORY FACTOR 2
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF AN IRF-2/DNA COMPLEX.
Length: 9
Consensus: AnGTgnAag
Weblogo: 
PSSM: P0      A      C      G      T
01     96      0      0      0      A
02     24     24     24     24      n
03      0      0     96      0      G
04      0      0      0     96      T
05     13     13     54     16      g
06     24     24     24     24      n
07     96      0      0      0      A
08     50     13     20     13      a
09     13     16     54     13      g
Binding TFs: 2irf_G / 2irf_H (Interferon regulatory factor transcription factor)
Binding Sites: 2irf_A
2irf_F
			
Publications: Fujii Y, Shimizu T, Kusumoto M, Kyogoku Y, Taniguchi T, Hakoshima T. Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences. The EMBO journal 18:5028-41 (1999). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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