DNA Binding Motif

Accessions: 5c8e_AF (3D-footprint 20231221)
Names: Light-dependent transcriptional regulator CarH
Organisms: strain HB27 / ATCC BAA-163 / DSM 7039, Thermus thermophilus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of Thermus thermophilus CarH bound to adenosylcobalamin and a 26-bp DNA segment
Length: 7
Consensus: TGTAnnT
01 9 9 11 67 T
02 0 0 96 0 G
03 0 0 0 96 T
04 67 9 11 9 A
05 24 24 24 24 n
06 24 24 24 24 n
07 9 9 9 69 T
Binding TFs: 5c8e_A (MerR family regulatory protein, B12 binding domain, MerR HTH family regulatory protein)
Publications: Jost M, Fernández-Zapata J, Polanco MC, Ortiz-Guerrero JM, Chen PY, Kang G, Padmanabhan S, Elías-Arnanz M, Drennan CL. Structural basis for gene regulation by a B12-dependent photoreceptor. Nature 526:536-41 (2015). [Pubmed]

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