DNA Binding Motif

Accessions: 2c6y_AB (3D-footprint 20231221)
Names: FORKHEAD BOX PROTEIN K2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of interleukin enhancer-binding factor 1 bound to DNA
Length: 11
Consensus: TAAACAATACA
Weblogo:
PSSM: P0 A C G T
01 1 6 0 89 T
02 96 0 0 0 A
03 90 0 6 0 A
04 68 6 6 16 A
05 6 75 6 9 C
06 78 6 6 6 A
07 96 0 0 0 A
08 0 0 0 96 T
09 90 0 0 6 A
10 0 96 0 0 C
11 96 0 0 0 A
Type: Heterodimer
Binding TFs: 2c6y_A (Fork head domain)
2c6y_B (Fork head domain)
Binding Sites: 2c6y_C
2c6y_D
Publications: Tsai K.L, Huang C.Y, Chang C.H, Sun Y.J, Chuang W.J, Hsiao C.D. Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins. The Journal of biological chemistry 281:17400-9 (2006). [Pubmed]

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