DNA Binding Motif

						

			
Accessions: MA0067.2 (JASPAR 2024)

			
Names: PAX2
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: CAP-SELEX
Length: 17
Consensus: bYArTsrwGCGTGACGr
Weblogo: 
PSSM: P0      A      C      G      T
01      5    948   1256   1366      b
02     67   2564     13   1010      Y
03   2808     48    767     43      A
04    972    851   1274    478      r
05     49    904     29   2671      T
06    261   1737   1837     28      s
07   2273      0   1301     27      r
08   2430     72    108   1145      w
09      4    727   2848     24      G
10      7   3575     22     44      C
11    352      8   3223     15      G
12     57     79    378   3197      T
13    718      3   2857      5      G
14   3575     26    168    237      A
15     79   3575     29     58      C
16    140    610   2965    260      G
17   1788    526   1787    592      r
Type: Heterodimer
Binding TFs: Q02962 ('Paired box' domain, Paired-box protein 2 C terminal)
Q02962
			
Publications: Epstein J., Cai J., Glaser T., Jepeal L., Maas R. Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes. J. Biol. Chem. 269:8355-8361 (1994). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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