DNA Binding Motif

						

			
Accessions: ZBTB7A_DBD (HumanTF 1.0), MA0750.1 (JASPAR 2024)

			
Names: ZBTB7A
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 12
Consensus: ggCGACCACCga
Weblogo: 
PSSM: P0      A      C      G      T
01     30     35     69     43      g
02     47     39    177     28      g
03      0    177     17      0      C
04     21      0    177      0      G
05    177     43      1      8      A
06      0    177      0      2      C
07      3    177      6      5      C
08    177     12      0      6      A
09      0    177      0      0      C
10     42    177      9     12      C
11     29     28     88     32      g
12     84     37     35     19      a
Type: Heterodimer
Binding TFs: O95365 (Zinc finger, C2H2 type, BTB/POZ domain, Zinc-finger double domain, C2H2-type zinc finger)
ZBTB7A_DBD (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
O95365
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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