DNA Binding Motif

						

			
Accessions: TEAD4_HOXA13_2_3 (HumanTF2 1.0)

			
Names: TEAD4_HOXA13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: rCATwCCrcrmmmscymrTAAA
Weblogo: 
PSSM: P0      A      C      G      T
01    218     39    165     12      r
02     96    383     16      0      C
03    383      3     41      0      A
04      0      9      0    383      T
05    152      1     57    231      w
06     30    383     44     16      C
07     26    383     19     98      C
08    160     51     98     74      r
09     95    133     73     82      c
10    121     81    102     79      r
11    112    114     84     73      m
12    132    134     38     79      m
13     99    129     67     88      m
14     51    121    130     81      s
15     35    258     74     16      c
16     41    191      1    192      y
17    116    173     15     80      m
18    176     11    153     43      r
19     66     22      4    383      T
20    383     20     14    117      A
21    383     29     15     37      A
22    383     85      9     51      A
Type: Heterodimer
Binding TFs: HOXA13_TF2 (Homeobox domain, Hox protein A13 N terminal)
HOXA13_Full (Homeobox domain, Hox protein A13 N terminal)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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