DNA Binding Motif

						

			
Accessions: E2F3_TBX21_2_3 (HumanTF2 1.0)

			
Names: E2F3_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: agGtGtgAatsGCGCsT
Weblogo: 
PSSM: P0      A      C      G      T
01    213     15     70     79      a
02     92     49    377     69      g
03     37     33    377     45      G
04     35    105     74    377      t
05      4      9    377      3      G
06     39     51     88    377      t
07     13    127    377    111      g
08    286     10     46     35      A
09    254     26     44     52      a
10     70     52     76    179      t
11     52    406    377    142      s
12      5      0    377      0      G
13      6    377     51     17      C
14      0      5    377      0      G
15      8    377    102     10      C
16     20    171    206     52      s
17     51     46     20    260      T
Type: Heterodimer
Binding TFs: TBX21_TF2 (T-box)
E2F3_TF1 (E2F/DP family winged-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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