DNA Binding Motif

						

			
Accessions: TFAP2C_ONECUT2_2 (HumanTF2 1.0)

			
Names: TFAP2C_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 25
Consensus: rrTCGATvygbttksCCygrGGskr
Weblogo: 
PSSM: P0      A      C      G      T
01    436     99    444     92      r
02   1071     43    435    138      r
03     28      2     28   1071      T
04     14   1071     14     62      C
05    333     24   1071     28      G
06   1071     30     34     92      A
07    120     96     28   1071      T
08    284    334    294    159      v
09    262    273    250    286      y
10    237    248    365    222      g
11    239    285    278    270      b
12    239    189    265    377      t
13    194    161    243    474      t
14    217    242    309    304      k
15    170    478   1071     58      s
16      0   1071      0      5      C
17      0   1071     18    108      C
18     86    619    387   1071      y
19    225    243    379    224      g
20    535    141    331     64      r
21    369     29   1071     35      G
22      0      0   1071      0      G
23     17    695    376     56      s
24    256    186    347    282      k
25    397    195    321    158      r
Type: Heterodimer
Binding TFs: ONECUT2_TF2 (Homeobox domain, CUT domain)
TFAP2C_TF1 (Transcription factor AP-2)
ONECUT2_Full (Homeobox domain, CUT domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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