DNA Binding Motif

						

			
Accessions: GCM2_SOX15_1 (HumanTF2 1.0)

			
Names: GCM2_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: aTrcGGGywykyyywTTGTtk
Weblogo: 
PSSM: P0      A      C      G      T
01    281     78     69      1      a
02     18     32     14    281      T
03     94      5    187      3      r
04     69    281    106     75      c
05     26      0    281     18      G
06      0      0    281      0      G
07      2      0    281      0      G
08     33    107     23    174      y
09    115     48     44     74      w
10     62     73     55     91      y
11     50     32    106     92      k
12     31     73     60    118      y
13     36    137     38     71      y
14     32    184      9     97      y
15    161      9     16    120      w
16     27      7      0    281      T
17     10      6     18    281      T
18     65     16    281     11      G
19     34     14      5    281      T
20     54     51     12    164      t
21     63     52     77     89      k
Type: Heterodimer
Binding TFs: GCM2_TF1 (GCM motif protein)
SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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