DNA Binding Motif

						

			
Accessions: PAX6_methyl_3 (HT-SELEX2 May2017)

			
Names: PAX6
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Length: 17
Consensus: tyaCGCwysAcyGmmym
Weblogo: 
PSSM: P0      A      C      G      T
01    480    332    486    996      t
02    291   1399     86    895      y
03   2294    431    508    216      a
04     16   2294     29    596      C
05    252     19   2294      0      G
06     75   2294    455     57      C
07    825    504    263    702      w
08    147    793     38   1500      y
09     72   1379    915    186      s
10   2294    152    789     20      A
11    494    878    389    532      c
12    140   1135     42   1159      y
13    763      0   2294    307      G
14    814   1480    417     45      m
15   1083    597    285    328      m
16     80   1624    132    670      y
17    707    675    411    501      m
Binding TFs: PAX6 (Homeobox domain, 'Paired box' domain)
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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