DNA Binding Motif

Accessions: MA1631.1 (JASPAR 2024)
Names: ASCL1, ASCL1(var.2)
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 13
Consensus: cdgCACCTGCysc
Weblogo:
PSSM: P0 A C G T
01 6833 11805 8371 7347 c
02 8952 7998 8601 8805 d
03 5836 6654 18576 3290 g
04 184 33562 321 289 C
05 32315 563 860 618 A
06 163 30169 3209 815 C
07 196 33402 607 151 C
08 368 740 492 32756 T
09 251 445 33411 249 G
10 399 28844 2719 2394 C
11 4490 17883 2966 9017 y
12 7083 10555 8939 7779 s
13 5972 11996 8356 8032 c
Type: Heterodimer
Binding TFs: P50553 (Helix-loop-helix DNA-binding domain)
P50553
Binding Sites: MA1631.1.10 / MA1631.1.6
MA1631.1.5 / MA1631.1.8
MA1631.1.1
MA1631.1.3
MA1631.1.11 / MA1631.1.7
MA1631.1.4
MA1631.1.6
MA1631.1.12 / MA1631.1.8
MA1631.1.13 / MA1631.1.9
MA1631.1.14
MA1631.1.10 / MA1631.1.15
MA1631.1.11 / MA1631.1.16
MA1631.1.12 / MA1631.1.17
MA1631.1.13 / MA1631.1.18
MA1631.1.14 / MA1631.1.19
MA1631.1.2
MA1631.1.15 / MA1631.1.20
MA1631.1.5
MA1631.1.7
MA1631.1.9
MA1631.1.19
MA1631.1.17
MA1631.1.20
MA1631.1.16
MA1631.1.18
MA1631.1.4
Publications: Aydin B, Kakumanu A, Rossillo M, Moreno-Estellés M, Garipler G, Ringstad N, Flames N, Mahony S, Mazzoni EO. Proneural factors Ascl1 and Neurog2 contribute to neuronal subtype identities by establishing distinct chromatin landscapes. Nat Neurosci 22:897-908 (2019). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.