DNA Binding Motif

Accessions: HOXB13_TBX21_2_3 (HumanTF2 1.0)
Names: HOXB13_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rgGTGTgAatTtATkr
Weblogo:
PSSM: P0 A C G T
01 311 40 183 104 r
02 70 101 240 104 g
03 4 24 311 34 G
04 24 35 7 311 T
05 2 0 311 18 G
06 54 64 11 311 T
07 12 58 216 95 g
08 311 35 74 30 A
09 100 74 59 77 a
10 62 62 59 311 t
11 68 2 0 311 T
12 115 29 35 311 t
13 311 17 34 43 A
14 23 91 8 311 T
15 65 11 134 101 k
16 89 21 154 47 r
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
TBX21_TF2 (T-box)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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