DNA Binding Motif

Accessions: 1zrf_A (3D-footprint 20231221)
Names: Catabolite gene activator
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: 4 crystal structures of CAP-DNA with all base-pair substitutions at position 6, CAP-[6C;17G]ICAP38 DNA
Length: 11
Consensus: CGnnnnnTGCG
Weblogo:
PSSM: P0 A C G T
01 9 69 9 9 C
02 9 9 67 11 G
03 24 24 24 24 n
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 24 24 24 24 n
08 9 9 11 67 T
09 0 0 96 0 G
10 0 96 0 0 C
11 0 0 96 0 G
Binding TFs: 1zrf_A (Cyclic nucleotide-binding domain, Bacterial regulatory proteins, crp family, Crp-like helix-turn-helix domain)
Binding Sites: 1zrf_W
1zrf_X
Publications: Napoli A.A, Lawson C.L, Ebright R.H, Berman H.M. Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps. Journal of molecular biology 357:173-83 (2006). [Pubmed]

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