DNA Binding Motif

						

			
Accessions: MGA_PITX1 (HumanTF2 1.0)

			
Names: MGA_PITX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: rgGTGyTAAkcyg
Weblogo: 
PSSM: P0      A      C      G      T
01    580     89    289    113      r
02    207    231    870    154      g
03      4     53    870     23      G
04     18    179     21    870      T
05     41     16    870      0      G
06    215    325     34    296      y
07    150      5     25    870      T
08    870      6      9      6      A
09    870      0     11      4      A
10     16     42    339    531      k
11    200    870    160    199      c
12    132    870    137    407      y
13    199    110    408    152      g
Type: Heterodimer
Binding TFs: MGA_TF1 (T-box)
PITX1_TF1 / PITX1_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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