DNA Binding Motif

						

			
Accessions: YY2_DBD (HumanTF 1.0), MA0748.1 (JASPAR 2024)

			
Names: YY2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 11
Consensus: gwcCGCCATtw
Weblogo: 
PSSM: P0      A      C      G      T
01    137     90    239     93      g
02    198     71     90    200      w
03     53    559     41    181      c
04      9    559     21     14      C
05     20     36    559     17      G
06     12    559      1      0      C
07      0    559      0      5      C
08    559      7      9     23      A
09      9      0      0    559      T
10     70     84     68    338      t
11    338     32    114    221      w
Type: Heterodimer
Binding TFs: YY2_DBD (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
O15391 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
O15391
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Kim J. D., Faulk C., Kim J. Retroposition and evolution of the DNA-binding motifs of YY1, YY2 and REX1.. Nucleic Acids Res. 35:3442-3452 (2007). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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