DNA Binding Motif

Accessions: 1u8b_A (3D-footprint 20231221)
Names: Ada polyprotein
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the methylated N-ADA/DNA complex
Length: 9
Consensus: AnnntArAT
Weblogo:
PSSM: P0 A C G T
01 96 0 0 0 A
02 24 24 24 24 n
03 24 24 24 24 n
04 24 24 24 24 n
05 18 18 22 38 t
06 91 1 4 0 A
07 50 0 24 22 r
08 96 0 0 0 A
09 13 0 6 77 T
Binding TFs: 1u8b_A (Bacterial regulatory helix-turn-helix proteins, AraC family, Metal binding domain of Ada, Helix-turn-helix domain)
Binding Sites: 1u8b_D
1u8b_E
Publications: He C, Hus J.C, Sun L.J, Zhou P, Norman D.P, Dötsch V, Wei H, Gross J.D, Lane W.S, Wagner G, Verdine G.L. A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada. Molecular cell 20:117-29 (2005). [Pubmed]

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