DNA Binding Motif

						

			
Accessions: HOXB2_TBX21_2 (HumanTF2 1.0)

			
Names: HOXB2_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: agGTGTkrrkmgymATTwrCAs
Weblogo: 
PSSM: P0      A      C      G      T
01    498     55    155    121      a
02    221    195    723    121      g
03     22     85    814     70      G
04      0    152     15    821      T
05      4      5    832     12      G
06    105    133     94    791      T
07    206    441    679    469      k
08    250    142    270    168      r
09    268    179    245    137      r
10    181    122    307    219      k
11    274    209    205    141      m
12    106    138    407    179      g
13    276    413    214    672      y
14    417    393     46    102      m
15    793     53    150     36      A
16      5     22     17    831      T
17     25     28      1    829      T
18    556     59     35    267      w
19    443     52    734    238      r
20     16    819     41     60      C
21    618      8    207     10      A
22     73    451    233     73      s
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
TBX21_TF2 (T-box)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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