DNA Binding Motif
| Accessions: | UP00008A_1 (UniPROBE 20160601) |
| Names: | Homeobox protein SIX6, Optic homeobox 2, Optx2, Sine oculis homeobox homolog 6, sine oculis-related homeobox 6 homolog (Drosophila), Six6, Six9, Six9 protein |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Length: | 17 |
| Consensus: | rwwrGGGTATCAhwtwt |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0.32 0.16 0.29 0.23 r 02 0.40 0.17 0.11 0.32 w 03 0.36 0.06 0.18 0.40 w 04 0.38 0.15 0.34 0.14 r 05 0.12 0.03 0.82 0.03 G 06 0.02 0.02 0.92 0.03 G 07 0.15 0.01 0.84 0 G 08 0 0 0.05 0.95 T 09 0.97 0 0.03 0 A 10 0 0 0 0.99 T 11 0.01 0.97 0 0.02 C 12 0.94 0.01 0.03 0.02 A 13 0.26 0.32 0.08 0.34 h 14 0.35 0.17 0.18 0.30 w 15 0.24 0.14 0.14 0.48 t 16 0.35 0.22 0.17 0.26 w 17 0.18 0.21 0.17 0.43 t |
| Binding TFs: | UP00008A (Homeobox domain, Homeobox KN domain) |
| Binding Sites: | AAGATATC AATGATAC AGATATCA AGGTATCA AGTATCAT AGTGATAC ATGATACC ATGATATC ATTGATAC CTGATATC GATACCCC GATATATC GATATCAA GATATCAC GATATCCC GGATATCA GGTATCAA GGTATCAC TGATATCA GATATCGC |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
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