DNA Binding Motif
| Accessions: | 1j46_A (3D-footprint 20231221) |
| Names: | SEX-DETERMINING REGION Y PROTEIN |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Description: | 3D Solution NMR Structure of the Wild Type HMG-BOX Domain of the Human Male Sex Determining Factor Sry Complexed to DNA |
| Length: | 7 |
| Consensus: | GTTTGTG |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0 0 96 0 G 02 0 0 0 96 T 03 9 7 7 73 T 04 9 7 7 73 T 05 7 9 73 7 G 06 0 0 0 96 T 07 9 7 73 7 G |
| Binding TFs: | 1j46_A (HMG (high mobility group) box, Domain of unknown function (DUF1898)) |
| Binding Sites: | 1j46_B 1j46_C |
| Publications: | Murphy E.C, Zhurkin V.B, Louis J.M, Cornilescu G, Clore G.M. Structural basis for SRY-dependent 46-X,Y sex reversal: modulation of DNA bending by a naturally occurring point mutation. Journal of molecular biology 312:481-99 (2001). [Pubmed] |
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