DNA Binding Motif

Accessions: 1by4_BC (3D-footprint 20231221)
Names: PROTEIN (RETINOIC ACID RECEPTOR RXR-ALPHA)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: STRUCTURE AND MECHANISM OF THE HOMODIMERIC ASSEMBLY OF THE RXR ON DNA
Length: 13
Consensus: GGTCAnnnGGTCA
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 0 0 96 0 G
03 9 9 9 69 T
04 0 96 0 0 C
05 67 9 9 11 A
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 0 0 96 0 G
10 0 0 96 0 G
11 0 0 0 96 T
12 0 96 0 0 C
13 69 9 9 9 A
Type: Heterodimer
Binding TFs: 1by4_B (Zinc finger, C4 type (two domains))
1by4_C (Zinc finger, C4 type (two domains))
Binding Sites: 1by4_E / 1by4_G
1by4_F / 1by4_H
Publications: Zhao Q, Chasse S.A, Devarakonda S, Sierk M.L, Ahvazi B, Rastinejad F. Structural basis of RXR-DNA interactions. Journal of molecular biology 296:509-20 (2000). [Pubmed]

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