DNA Binding Motif

						

			
Accessions: E2F1_ELK1_2 (HumanTF2 1.0)

			
Names: E2F1_ELK1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 22
Consensus: sGCGcshwtwkggrsCGGAAGt
Weblogo: 
PSSM: P0      A      C      G      T
01    116    619    632     65      s
02     35     67   1251     47      G
03     24   1251     81     50      C
04     37     64   1251     61      G
05     52   1251    379    189      c
06    109    438    519    186      s
07    349    367    189    346      h
08    361    203    270    416      w
09    296    261    267    426      t
10    315    272    295    369      w
11    222    305    359    366      k
12    256    237    478    280      g
13    282    259    414    295      g
14    534     73    471    173      r
15    217    594    349     90      s
16    157   1251     97     56      C
17      3      2   1251      0      G
18     17     16   1251     27      G
19   1251     20     45     52      A
20   1251     50     54    242      A
21    185    145   1251     23      G
22     87    200    159    804      t
Type: Heterodimer
Binding TFs: E2F1_TF1 (E2F/DP family winged-helix DNA-binding domain)
ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
ELK1_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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