DNA Binding Motif

						

			
Accessions: PBX4_HOXA10_2_3 (HumanTF2 1.0)

			
Names: PBX4_HOXA10
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: cycrTAAATCamTCa
Weblogo: 
PSSM: P0      A      C      G      T
01    161    212    146    128      c
02     91    163     23    145      y
03     70    207     76     69      c
04    265     22    143      8      r
05     41     22      8    390      T
06    405     64     31     42      A
07    413     83      0     33      A
08    418     29     17      1      A
09     10      0      0    418      T
10     29    419      0      0      C
11    374    108     20     58      a
12    367    175     47     71      m
13     53     57     24    385      T
14     45    400     49     38      C
15    372     84    114     53      a
Type: Heterodimer
Binding TFs: HOXA10_TF2 (Homeobox domain)
PBX4_TF1 (Homeobox domain, PBC domain, Homeobox KN domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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