DNA Binding Motif

						

			
Accessions: ETV5_HOXA2_2_3 (HumanTF2 1.0)

			
Names: ETV5_HOXA2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: rsCGGwArTkr-
Weblogo: 
PSSM: P0      A      C      G      T
01   1289    208   1082    425      r
02    553   1461    910    160      s
03    594   2371    144    143      C
04     22     68   2371     24      G
05     85    130   2371    193      G
06   1494     55      0    876      w
07   2371     60      0    193      A
08   2371    190   1610     23      r
09     42    384    305   2371      T
10    168    363   1384    986      k
11   1203    338   1168    401      r
12      0      0      0      0      -
Type: Heterodimer
Binding TFs: ETV5_TF1 (Ets-domain)
HOXA2_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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