DNA Binding Motif

						

			
Accessions: HOXB2_ELK3_2 (HumanTF2 1.0)

			
Names: HOXB2_ELK3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: TrAygkgwacCGGAAGTr
Weblogo: 
PSSM: P0      A      C      G      T
01     84     35     33    419      T
02    419      7    207     30      r
03    419      0     12      1      A
04      2    216      8    419      y
05    132    122    419    145      g
06     93     77    122    128      k
07     81     84    191     63      g
08    185     52     65    117      w
09    220     55     64     81      a
10    100    185     53     82      c
11     48    419      0     12      C
12      0      0    419      0      G
13      0      5    419      0      G
14    419      1      1     16      A
15    419     20      1     84      A
16    118     64    419      6      G
17     45    104     42    419      T
18    151     61    175     33      r
Type: Heterodimer
Binding TFs: ELK3_TF2 (Ets-domain)
HOXB2_TF1 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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