DNA Binding Motif

						

			
Accessions: E2F3_TBX21_1 (HumanTF2 1.0)

			
Names: E2F3_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: agGTGtsAdgGCGCst
Weblogo: 
PSSM: P0      A      C      G      T
01    202     54     94     42      a
02    160    113    392     86      g
03     30     13    392    111      G
04      4     78     11    392      T
05      5      0    392      0      G
06     87    155     42    392      t
07     59    267    392    201      s
08    389      0      0      4      A
09    147     11    118    117      d
10     67    148    392     73      g
11      0      5    392     78      G
12     33    392     61     20      C
13      9     10    392      9      G
14     15    392     75     73      C
15     22    179    213     60      s
16     55     56     61    221      t
Type: Heterodimer
Binding TFs: TBX21_TF2 (T-box)
E2F3_TF1 (E2F/DP family winged-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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