DNA Binding Motif

Accessions: UP00411A_1 (UniPROBE 20160601)
Names: avian erythroblastosis virus E-26 (v-ets) oncogene related, D030036I24Rik, Erg, Erg-3, Transcriptional regulator ERG
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: vtsmAyTTCCGGtwkc
Weblogo:
PSSM: P0 A C G T
01 0.30 0.28 0.26 0.16 v
02 0.12 0.23 0.24 0.40 t
03 0.15 0.29 0.35 0.21 s
04 0.32 0.33 0.18 0.17 m
05 0.78 0.01 0.20 0.01 A
06 0 0.58 0.01 0.40 y
07 0.11 0 0 0.89 T
08 0.01 0 0 0.99 T
09 0 0.99 0 0 C
10 0 0.99 0 0 C
11 0 0 0.89 0.10 G
12 0.01 0.03 0.94 0.02 G
13 0.19 0.12 0.04 0.66 t
14 0.30 0.20 0.22 0.28 w
15 0.19 0.17 0.31 0.34 k
16 0.16 0.41 0.20 0.24 c
Binding TFs: UP00411A (Ets-domain)
Binding Sites: AACCGGAA
ACATCCGG
ACCGGAAA
ACCGGAAG
ACCGGATG
ACTTCCGG
ATCCGGAA
CACCGGAA
CACTTCCG
CATTTCCG
CCGGAAAC
CCGGAAGC
CCGGATGC
CTTCCGGA
CTTCCGGC
GACCGGAA
GCCGGAAA
TACCGGAA
TCCGGAAA
TTCCGGAA
Publications: Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed]

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