DNA Binding Motif

						

			
Accessions: 6oem_BCH (3D-footprint 20231221)

			
Names: High mobility group protein B1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Cryo-EM structure of mouse RAG1/2 PRC complex (DNA0)
Length: 18
Consensus: GTTaAGnnnnnnannmCT
Weblogo: 
PSSM: P0      A      C      G      T
01      5      1     76     14      G
02      0      0      0     96      T
03      4      1      9     82      T
04     65      9      9     13      a
05     92      1      3      0      A
06      0      0     96      0      G
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12     24     24     24     24      n
13     63     11     13      9      a
14     24     24     24     24      n
15     24     24     24     24      n
16     41     29     15     11      m
17      0     96      0      0      C
18      0      0      0     96      T
Binding TFs: 6oem_H (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: 6oem_F
6oem_I
			
Publications: Chen X, Cui Y, Best RB, Wang H, Zhou ZH, Yang W, Gellert M. Cutting antiparallel DNA strands in a single active site. Nat Struct Mol Biol 27:119-126 (2020). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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