DNA Binding Motif

						

			
Accessions: TEAD4_HOXB13_2_3_4 (HumanTF2 1.0)

			
Names: TEAD4_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: rGAATGCaaTaAA
Weblogo: 
PSSM: P0      A      C      G      T
01    110      5    122      2      r
02     38     17    194     23      G
03    231     25     12     26      A
04    231      2      0      3      A
05     14      4      2    231      T
06      0      5    231      0      G
07      0    231      0     43      C
08    231     58     24     58      a
09    175     32     56      0      a
10     14     12      3    231      T
11    231     28     29     56      a
12    231     19     16      4      A
13    231     16     14     50      A
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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