DNA Binding Motif

Accessions: 4bhk_AB (3D-footprint 20231221)
Names: FLORICAULA/LEAFY HOMOLOG 1
Organisms: Physcomitrella patens, Physcomitrium patens (Spreading-leaved earth moss)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of Moss Leafy bound to DNA
Length: 18
Consensus: GGnCGACCnnnGGrCGgT
Weblogo:
PSSM: P0 A C G T
01 7 3 81 5 G
02 3 2 86 5 G
03 24 24 24 24 n
04 0 96 0 0 C
05 1 1 77 17 G
06 72 10 7 7 A
07 0 96 0 0 C
08 0 96 0 0 C
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 0 0 96 0 G
13 0 0 96 0 G
14 49 0 47 0 r
15 21 69 3 3 C
16 0 0 96 0 G
17 13 5 65 13 g
18 4 5 5 82 T
Binding TFs: 4bhk_A / 4bhk_B (Floricaula / Leafy protein)
Binding Sites: 4bhk_W
4bhk_X
Publications: Sayou C, Monniaux M, Nanao M.H, Moyroud E, Brockington S.F, Thévenon E, Chahtane H, Warthmann N, Melkonian M, Zhang Y, Wong G.K, Weigel D, Parcy F, Dumas R. A promiscuous intermediate underlies the evolution of LEAFY DNA binding specificity. Science (New York, N.Y.) 343:645-8 (2014). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.