DNA Binding Motif

						

			
Accessions: FOXJ2_PITX1_1 (HumanTF2 1.0)

			
Names: FOXJ2_PITX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: yTAATCCcdamAAcA
Weblogo: 
PSSM: P0      A      C      G      T
01     51    160     36    140      y
02     16     39     15    387      T
03    387      0     16     32      A
04    387      0      0     46      A
05      0      0      0    387      T
06      0    387     26      0      C
07      0    387     36     51      C
08     60    194     81     53      c
09    129     41    114    104      d
10    274     58     70    113      a
11    181    206     16     37      m
12    387     86     21     18      A
13    387     11     67     77      A
14    135    387     28     69      c
15    387      0    103     62      A
Type: Heterodimer
Binding TFs: PITX1_TF1 / PITX1_TF2 (Homeobox domain)
FOXJ2_TF1 (Fork head domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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