DNA Binding Motif

						

			
Accessions: UP00595C_1 (UniPROBE 20160601)

			
Names: HHO.C1, Homeobox protein HHO.C1, Homeobox protein Hox-2C, homeobox protein Hox-B7, Hox-2.3, HOX2, HOX2C, HOXB7_M190L_R1
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 23
Consensus: TwasksyATAATTAtwGgtwkdr
Weblogo: 
PSSM: P0      A      C      G      T
01   0.12   0.10   0.06   0.71      T
02   0.36   0.07   0.16   0.42      w
03   0.43   0.19   0.22   0.16      a
04   0.15   0.30   0.31   0.24      s
05   0.23   0.10   0.41   0.26      k
06   0.24   0.31   0.34   0.10      s
07   0.13   0.37   0.18   0.32      y
08   0.79   0.03   0.14   0.04      A
09   0.03   0.07   0.02   0.88      T
10   0.78   0.03   0.07   0.12      A
11   0.83   0.06   0.07   0.04      A
12   0.11   0.11   0.02   0.76      T
13   0.09   0.05   0.03   0.82      T
14   0.75   0.06   0.14   0.05      A
15   0.20   0.18   0.09   0.53      t
16   0.32   0.21   0.19   0.28      w
17   0.16   0.10   0.68   0.06      G
18   0.22   0.20   0.33   0.24      g
19   0.23   0.16   0.20   0.41      t
20   0.51   0.14   0.08   0.27      w
21   0.15   0.09   0.32   0.43      k
22   0.39   0.04   0.30   0.27      d
23   0.36   0.12   0.37   0.15      r
Binding TFs: UP00595C (Homeobox domain)
Binding Sites: AAATATAT
AATATATT
ATAATATA
ATAATTAT
ATAATTGA
ATATATTA
ATATTAAT
ATATTATG
CATAATTA
GTAATTAC
TAATTATA
TATATATA
TATTAATA
AATATGAT
ACATATTC
AGTATATA
ATAATACA
ATAATCAT
ATACATAT
TATATACA
			
Publications: Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science 351:1450-4 (2016). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.