DNA Binding Motif

						

			
Accessions: ETV2_HOXA2_2 (HumanTF2 1.0)

			
Names: ETV2_HOXA2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: rcCGGAwryrawrgymATTA
Weblogo: 
PSSM: P0      A      C      G      T
01   4112    832   2398   1287      r
02   1859   7210   2125    577      c
03   1488   8252    205     27      C
04     13      0   8631      0      G
05     33      9   8635      0      G
06   8589     71      0    129      A
07   7440    577     52   3610      w
08   3605    659   7311     98      r
09    885   2682   1428   3633      y
10   3175   1384   2575   1495      r
11   3636   1596   1879   1517      a
12   2617   1520   1853   2638      w
13   2500   1663   2395   2071      r
14   1767   2085   3596   1180      g
15   1481   3530   1349   4539      y
16   3917   4041   1787    640      m
17   7942   1524   1285    543      A
18    227    427    181   8584      T
19    630   1399    298   8211      T
20   8321    412    515   1591      A
Type: Heterodimer
Binding TFs: HOXA2_TF2 (Homeobox domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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