DNA Binding Motif

						

			
Accessions: ELK1_EOMES_2 (HumanTF2 1.0), UN0494.1 (JASPAR 2024)

			
Names: ELK1_EOMES, ELK1::EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 17
Consensus: rcCGGAAGTrgGyGygA
Weblogo: 
PSSM: P0      A      C      G      T
01    232     16    154     33      r
02     28    286    100     14      c
03     25    386      7      5      C
04      1      0    386      1      G
05      1      1    386      3      G
06    386      0      9      1      A
07    386      1      8     14      A
08     13     55    318      0      G
09      8     62     21    294      T
10    386     76    275     72      r
11    105    103    386    106      g
12     30     55    386     48      G
13     22    128     19    258      y
14     41      7    386     16      G
15     59    155     75    231      y
16     59     88    157     82      g
17    386     33    101     43      A
Type: Heterodimer
Binding TFs: P19419 (Ets-domain)
ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
EOMES_TF2 (T-box)
ELK1_TF1 (Ets-domain)
P19419
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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